The changes in the civil construction context, and consequently the production management of constructions, require a different profile engineer, which demands more refined skills from those professionals, such as innovation, focus on customer, production planning and control, quality management systems knowledge, sustainability and a humanist visi
Challenges of Health System Reform Plan in Bushehr: A Qualitative Study
Background: The health system reform plan was implemented by the Ministry of Health and Medical Education in accordance with the Fourth and Fifth Development Plan Acts in order to achieve public health coverage.Despite achieving many successes in the pursuit of the objectives of the plan, it has faced challenges.The purpose of the study was to dete
Spatial distribution of, and risk factors for, Opisthorchis viverrini infection in southern Lao PDR.
BACKGROUND: Opisthorchis viverrini is a food-borne trematode species that might give rise to biliary diseases and the fatal cholangiocarcinoma.In Lao PDR, an estimated 2.5 million individuals are infected with O.viverrini, but epidemiological studies are scarce and the spatial distribution of infection remains to be determined.Our aim was to map th
VAP-mediated membrane-tethering mechanisms implicate ER-PM contact function in pH homeostasis
Back Console Housing Summary: Vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) are highly conserved endoplasmic reticulum (ER)-resident proteins that establish ER contacts with multiple membrane compartments in many eukaryotes.However, VAP-mediated membrane-tethering mechanisms remain ambiguous.Here, focusing on fission yeast E
Bile Acids: Key Regulators and Novel Treatment Targets for Type 2 Diabetes
Type 2 diabetes mellitus (T2DM), characterized by insulin resistance and unclear pathogenesis, is a serious menace to human health.Bile acids are the end products of cholesterol catabolism and play an important role in maintaining cholesterol homeostasis.Furthermore, increasing studies suggest that Health bile acids may regulate glucose tolerance,